A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles

A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles.

Merging acoustofluidic mixing with optofluidic integration, we have demonstrated a single-layer, planar, optofluidic switch that is driven by acoustically excited oscillating microbubbles. The device was found to have a switching speed of 5 Hz, an insertion loss of 6.02 dB, and an extinction ratio of 28.48 dB. With its simplicity, low fluid consumption, and compatibility with other microfluidic...

Acoustically driven planar microfluidics

Surface acoustic waves are used to actuate and process smallest possible amounts of fluids on the planar surface of a piezoelectric chip. Chemical modification of the chip surface is employed to create virtual wells and tubes to confine the liquids. Lithographically modulated wetting properties of the surface define a fluidic network, in analogy to the wiring of an electronic circuit. Acoustic ...

Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles.

We present a novel concept of generating both static and pulsatile chemical gradients using acoustically activated bubbles designed in a ladder-like arrangement. Furthermore, by regulating the amplitude of the bubble oscillation, we demonstrate that the chemical gradient profiles can be effectively tuned.

A single-layer, planar, optofluidic Mach-Zehnder interferometer for label-free detection.

We have developed a planar, optofluidic Mach-Zehnder interferometer for the label-free detection of liquid samples. In contrast to most on-chip interferometers which require complex fabrication, our design was realized via a simple, single-layer soft lithography fabrication process. In addition, a single-wavelength laser source and a silicon photodetector were the only optical equipment used fo...

Enhancement of Focused Ultrasound Treatment by Acoustically Generated Microbubbles